GO:0016580 cellular_component Sin3 complex
| PAG Title | GO:0016580 cellular_component Sin3 complex |
| PAG ID | TAX019106 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 1,748 |
| Information Content | Rich |
| Other IDs | GO:0016580 |
| Base PAG ID | TAX019106 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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